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. The yeast Saccharomyces cerevisiae possesses a finite lifespan; the metric of which is the number of times the cell divides and not its chronological age (1). The free radical theory of ageing postulates that reactive oxygen species are causal factors in ageing (2). These species are capable of damaging DNA, protein and lipids within the cell. For defence against these prooxidants, cells contain antioxidant molecule such as glutathione (GSH).

Glutathione Biosynthesis Influences Replicative Longevity in Saccharomyces Cerevisiae