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Serotonin Receptors in Hippocampus
Author(s) -
Laura C. Berumen,
Angelina Rodríguez,
Ricardo Miledi,
Guadalupe GarcíaAlcocer
Publication year - 2012
Publication title -
the scientific world journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.453
H-Index - 93
eISSN - 2356-6140
pISSN - 1537-744X
DOI - 10.1100/2012/823493
Subject(s) - serotonin , neuroscience , hippocampus , 5 ht receptor , receptor , postsynaptic potential , neurotransmitter , serotonergic , neurotransmitter receptor , biology , central nervous system , biochemistry
Serotonin is an ancient molecular signal and a recognized neurotransmitter brainwide distributed with particular presence in hippocampus. Almost all serotonin receptor subtypes are expressed in hippocampus, which implicates an intricate modulating system, considering that they can be localized as autosynaptic, presynaptic, and postsynaptic receptors, even colocalized within the same cell and being target of homo- and heterodimerization. Neurons and glia, including immune cells, integrate a functional network that uses several serotonin receptors to regulate their roles in this particular part of the limbic system.

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