English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Intensive gene targeting studies in mice have revealed that prolyl hydroxylase domain proteins (PHDs) play important roles in murine embryonic development; however, the expression patterns and function of these genes during embryogenesis of other vertebrates remain largely unknown. Here we report the molecular cloning of  phd1  and systematic analysis of  phd1 ,  phd2 , and  phd3  expression in embryos as well as adult tissues of  Xenopus laevis . All three  phds  are maternally provided during  Xenopus  early development. The spatial expression patterns of  phds  genes in  Xenopus  embryos appear to define a distinct synexpression group. Frog  phd2  and  phd3  showed complementary expression in adult tissues with  phd2  transcription levels being high in the eye, brain, and intestine, but low in the liver, pancreas, and kidney. On the contrary, expression levels of  phd3  are high in the liver, pancreas, and kidney, but low in the eye, brain, and intestine. All three  phds  are highly expressed in testes, ovary, gall bladder, and spleen. Among three  phds ,  phd3  showed strongest expression in heart.

Molecular Cloning ofphd1and Comparative Analysis ofphd1, 2, and3Expression inXenopus laevis