Zinc Oxide Nanoparticles Catalyzed Condensation Reaction of Isocoumarins and 1,7-Heptadiamine in the Formation of Bis-Isoquinolinones | Zendy

Varadhan Krishnakumar | Zendy; Mohan Kumar Kesarla | Zendy; Badal Kumar Mandal | Zendy; FazlurRahman Nawaz Khan | Zendy

Open Access

Zinc Oxide Nanoparticles Catalyzed Condensation Reaction of Isocoumarins and 1,7-Heptadiamine in the Formation of Bis-Isoquinolinones

Author(s) -

Varadhan Krishnakumar,

Mohan Kumar Kesarla,

Badal Kumar Mandal,

FazlurRahman Nawaz Khan

Publication year - 2012

Publication title -

the scientific world journal

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.453

H-Index - 93

eISSN - 2356-6140

pISSN - 1537-744X

DOI - 10.1100/2012/619080

Subject(s) - isocoumarins , zinc , chemistry , yield (engineering) , nanoparticle , catalysis , condensation , fourier transform infrared spectroscopy , condensation reaction , nuclear chemistry , organic chemistry , materials science , nanotechnology , chemical engineering , physics , engineering , metallurgy , thermodynamics

The diversified bis-isoquinolinones were obtained in two steps, utilizing homophthalic acid and various acid chlorides providing 3-substituted isocoumarins in the first step which on further condensation with 1,7-heptadiamine involving C–N bond formation from the lactone in the presence of 10 mol% zinc oxide nanoparticles (ZnO NPs) (<150 nm) afforded the desired bis-isoquinolinones in high yield and purity. The synthesized compounds were then characterized using FTIR, 1 H NMR, 13 C NMR, and HRMS techniques.

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