Microbial Transformations of 7-Hydroxyflavanone | Zendy

Edyta Kostrzewa-Susłow | Zendy; Tomasz Janeczko | Zendy

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Microbial Transformations of 7-Hydroxyflavanone

Author(s) -

Edyta Kostrzewa-Susłow,

Tomasz Janeczko

Publication year - 2012

Publication title -

the scientific world journal

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.453

H-Index - 93

eISSN - 2356-6140

pISSN - 1537-744X

DOI - 10.1100/2012/254929

Subject(s) - hydroxylation , aspergillus niger , dehydrogenation , aspergillus ochraceus , methylation , chemistry , carbonyl group , biotransformation , penicillium , medicinal chemistry , organic chemistry , food science , biochemistry , catalysis , enzyme , mycotoxin , ochratoxin a , gene

Microbial transformations of racemic 7-hydroxyflavanone using strains of genus Aspergillus (A. niger KB, A. niger 13/5, A. ochraceus 456) and the species Penicillium chermesinum 113 were studied. The products of O -methylation, O -methylation along with hydroxylation at C-3′ and C-4′, reduction of the carbonyl group, reduction of the carbonyl group along with hydroxylation at C-5, and dehydrogenation of C-2 and C-3 were obtained. Most of the products (with the exception of the O -methylation one) have stronger antioxidant properties than the initial substrate.

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