Two suppressors of RNA silencing encoded by cereal-infecting members of the family Luteoviridae | Zendy

Yàn Liú | Zendy; Hao Zhai | Zendy; Kun Zhao | Zendy; Beilei Wu | Zendy; Xifeng Wang | Zendy

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Two suppressors of RNA silencing encoded by cereal-infecting members of the family Luteoviridae

Author(s) -

Yàn Liú,

Hao Zhai,

Kun Zhao,

Beilei Wu,

Xifeng Wang

Publication year - 2012

Publication title -

journal of general virology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.55

H-Index - 167

eISSN - 1465-2099

pISSN - 0022-1317

DOI - 10.1099/vir.0.042135-0

Subject(s) - biology , luteovirus , nicotiana benthamiana , barley yellow dwarf , gene silencing , rna silencing , virology , genetics , gene , potato virus x , rna induced transcriptional silencing , plant virus , rna , virus , microbiology and biotechnology , rna interference

Several members of the family Luteoviridae are important pathogens of cultivated plant species of the family Gramineae. In this study, we explored RNA-silencing suppressors (RSSs) encoded by two cereal-infecting luteoviruses: barley yellow dwarf virus and wheat yellow dwarf virus (BYDV and WYDV, respectively). The P0 protein of WYDV-GPV (P0(GPV)) and the P6 protein of BYDV-GAV (P6(GAV)) displayed RSS activities when expressed in agro-infiltrated leaves of Nicotiana benthamiana, by their local ability to inhibit post-transcriptional gene silencing of GFP. Analysis of GFP, mRNA and GFP-specific small interfering RNA indicated that both P0(GPV) and P6(GAV) are suppressors of silencing that can restrain not only local but also systemic gene silencing. This is the first report of RSS activity of the P6 protein in a member of the genus Luteovirus.

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