Open AccessGenomic and phylogenetic characterization of Leanyer virus, a novel orthobunyavirus isolated in northern Australia
Author(s) -
Nazir Savji,
Gustavo Palacios,
Amélia Travassos da Rosa,
Stephen Hutchison,
Christopher Celone,
Jeffrey Hui,
Thomas Briese,
Charles H. Calisher,
Robert B. Tesh,
W. Ian Lipkin
Publication year - 2011
Publication title -
journal of general virology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.55
H-Index - 167
eISSN - 1465-2099
pISSN - 0022-1317
DOI - 10.1099/vir.0.028308-0
Subject(s) - biology , orthobunyavirus , phylogenetic tree , virology , phylogenetics , virus , genetics , evolutionary biology , gene
Leanyer virus (LEAV), currently classified as a member of the genus Orthobunyavirus, in the family Bunyaviridae, was originally isolated from a pool of Anopheles meraukensis mosquitoes, collected at Leanyer, Northern Territory, Australia in 1974. When it failed to react in serological tests with antisera from other known viruses, full-length genomic sequencing was pursued to determine the relationship of LEAV to other orthobunyavirus species. Genetic and serological characterization confirmed its antigenic distance from other orthobunyaviruses, including to its closest genetic neighbours, the Simbu group viruses, suggesting that it may represent a new antigenic complex.
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