Innate immunity and the pneumococcus
Author(s) -
Gavin K. Paterson,
Timothy J. Mitchell
Publication year - 2006
Publication title -
microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.019
H-Index - 179
eISSN - 1465-2080
pISSN - 1350-0872
DOI - 10.1099/mic.0.28551-0
Subject(s) - innate immune system , streptococcus pneumoniae , acquired immune system , biology , immune system , first line , effector , immunity , immunology , pneumococcal infections , pathogen , microbiology and biotechnology , medicine , antibiotics
The innate immune system provides a non-specific first line of defence against microbes and is crucial both in the development and effector stages of subsequent adaptive immune responses. Consistent with its importance, study of the innate immune system is a broad and fast-moving field. Here we provide an overview of the recent key advances made in this area with relation to the important pathogen Streptococcus pneumoniae (the pneumococcus).
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