Open AccessSevere case of Mediterranean spotted fever in Greece with predominantly neurological features
Author(s) -
K Tzavella,
Ioannis S. Hatzizisis,
Aikaterini Vakali,
K. Mandraveli,
Dimitrios Zioutas,
Stella AlexiouDaniel
Publication year - 2006
Publication title -
journal of medical microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.91
H-Index - 117
eISSN - 1473-5644
pISSN - 0022-2615
DOI - 10.1099/jmm.0.46337-0
Subject(s) - rickettsia conorii , spotted fever , boutonneuse fever , rickettsiosis , doxycycline , antibiotics , mediterranean climate , rickettsia , antibody , medicine , indirect immunofluorescence , virology , immunology , biology , microbiology and biotechnology , serology , virus , ecology
Rickettsia conorii is endemic in Greece, though only a few cases of infection have been published to date. The case of a 58-year-old man from northern Greece with a severe form of Mediterranean spotted fever and rapid neurological deterioration is presented here. The patient received antibiotic treatment with doxycycline, showing immediate clinical and laboratory improvement. Diagnosis was confirmed later, during the second week after disease onset, by detection of elevated titres of IgM and IgG antibodies against R. conorii using an indirect immunofluorescence assay.
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