Open AccessFatal pulmonary infection in a leukaemic patient caused by Hormographiella aspergillata
Author(s) -
Katrien Lagrou,
Caroline Massonet,
Koen Theunissen,
Wouter Meersseman,
M. Lontie,
Eric Verbeken,
Johan Van Eldere,
Johan Maertens
Publication year - 2005
Publication title -
journal of medical microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.91
H-Index - 117
eISSN - 1473-5644
pISSN - 0022-2615
DOI - 10.1099/jmm.0.46016-0
Subject(s) - caspofungin , autopsy , galactomannan , bronchoalveolar lavage , pneumonia , aspergillus , fungus , aspergillosis , pathology , medicine , microbiology and biotechnology , lung , biology , immunology , amphotericin b , antifungal , botany
A case of autopsy-proven fungal pneumonia in a relapsed leukaemia patient is reported. The fungus Hormographiella aspergillata was cultured from two bronchoalveolar fluid samples and identified through morphological examination and ITS2 sequence analysis. In addition, galactomannan was detected in eight consecutive serum samples, which suggested a co-infection with Aspergillus species. The patient was treated with caspofungin.
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