Open AccessIsolated high-level ciprofloxacin resistance in Salmonella enterica subsp. enterica serotype Paratyphi A
Author(s) -
B. N. Harish,
U. Madhulika,
SC Parija
Publication year - 2004
Publication title -
journal of medical microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.91
H-Index - 117
eISSN - 1473-5644
pISSN - 0022-2615
DOI - 10.1099/jmm.0.05451-0
Subject(s) - salmonella enterica , microbiology and biotechnology , serotype , ciprofloxacin , clinical microbiology , biology , salmonella , antibiotics , bacteria , genetics
A 23-year-old male was diagnosed as suffering from enteric fever at JIPMER, Pondicherry. Salmonella enterica subsp. enterica serotype Paratyphi A was isolated by blood culture. This strainwas found to be susceptible to all antibiotics by disc diffusion, except ciprofloxacin. TheMIC for ciprofloxacin as determined by both agar and broth dilutionmethods was found to be 8 mg l . This exceeds the limit set for resistance by NCCLS, which is 4 mg l 1 (NCCLS, 1973). Resistance to ciprofloxacin has not been reported so far in the enteric fever salmonellae; this is the first report of S. Paratyphi A with an MIC of 8 mg l .
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