In vitro detection of bacterial contamination in platelet concentrates by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry: a preliminary study | Zendy

Yasmine Chetouane | Zendy; G Dubourg | Zendy; Pierre Gallian | Zendy; Jérémy Delerce | Zendy; Anthony Levasseur | Zendy; Christophe Flaudrops | Zendy; Éric Chabrière | Zendy; Jacques Chiaroni | Zendy; Didier Raoult | Zendy; Laurence CamoinJau | Zendy

Open Access

In vitro detection of bacterial contamination in platelet concentrates by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry: a preliminary study

Author(s) -

Yasmine Chetouane,

G Dubourg,

Pierre Gallian,

Jérémy Delerce,

Anthony Levasseur,

Christophe Flaudrops,

Éric Chabrière,

Jacques Chiaroni,

Didier Raoult,

Laurence CamoinJau

Publication year - 2017

Publication title -

journal of medical microbiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.91

H-Index - 117

eISSN - 1473-5644

pISSN - 0022-2615

DOI - 10.1099/jmm.0.000533

Subject(s) - contamination , mass spectrometry , desorption , chemistry , matrix (chemical analysis) , matrix assisted laser desorption/ionization , surface enhanced laser desorption/ionization , environmental chemistry , ionization , chromatography , time of flight mass spectrometry , analytical chemistry (journal) , biology , sample preparation in mass spectrometry , ion , organic chemistry , electrospray ionization , ecology , adsorption

Platelet concentrates are at risk of transfusion-related sepsis. The microbial detection methods currently available have reached their limits, as they do not completely prevent transfusion-related bacterial contamination.The aim of this study was to develop a new strategy to detect the risk of platelet transfusion-related bacterial contamination using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS).

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