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The objective of the present study was to investigate whether Streptococcus sanguinis SpxA2 plays a role in competence development and endogenous H2O2 generation, and whether the SpxA2 Cys10-XX-Cys13 (CXXC) motif is involved in competence development.

Is SpxA2 involved in hydrogen peroxide production and competence development in Streptococcus sanguinis?