Open AccessExposure to sub-inhibitory concentrations of gentamicin, ciprofloxacin and cefotaxime induces multidrug resistance and reactive oxygen species generation in meticillin-sensitive Staphylococcus aureus
Author(s) -
Gargi Bhattacharya,
Diganta Dey,
Satadal Das,
Abhijit Banerjee
Publication year - 2017
Publication title -
journal of medical microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.91
H-Index - 117
eISSN - 1473-5644
pISSN - 0022-2615
DOI - 10.1099/jmm.0.000492
Subject(s) - ciprofloxacin , staphylococcus aureus , cefotaxime , gentamicin , microbiology and biotechnology , multiple drug resistance , minimum inhibitory concentration , antibiotics , antibacterial agent , chemistry , biology , bacteria , genetics
The role of antibiotics below their MIC in the development of bacterial drug resistance is becoming increasingly important. We investigated the effect of sub-MICs of bactericidal antibiotics on the susceptibility pattern of Staphylococcus aureus and evaluated the role of free radicals.
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