Recombinant esterase from Corynebacterium pseudotuberculosis in DNA and subunit recombinant vaccines partially protects mice against challenge | Zendy

Alexandre Antunes Brum | Zendy; Andréa de Fátima Silva Rezende | Zendy; Francisco Silvestre Brilhante | Zendy; Thaís Farias Collares | Zendy; Karine Begnine | Zendy; Fabiana K. Seixas | Zendy; Tiago Collares | Zendy; Odir Antônio Dellagostin | Zendy; Vasco Azevedo | Zendy; Anderson Rodrigues dos Santos | Zendy; Ricardo Wagner Portela | Zendy; Sibele Borsuk | Zendy

Open Access

Recombinant esterase from Corynebacterium pseudotuberculosis in DNA and subunit recombinant vaccines partially protects mice against challenge

Author(s) -

Alexandre Antunes Brum,

Andréa de Fátima Silva Rezende,

Francisco Silvestre Brilhante,

Thaís Farias Collares,

Karine Begnine,

Fabiana K. Seixas,

Tiago Collares,

Odir Antônio Dellagostin,

Vasco Azevedo,

Anderson Rodrigues dos Santos,

Ricardo Wagner Portela,

Sibele Borsuk

Publication year - 2017

Publication title -

journal of medical microbiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.91

H-Index - 117

eISSN - 1473-5644

pISSN - 0022-2615

DOI - 10.1099/jmm.0.000477

Subject(s) - recombinant dna , corynebacterium pseudotuberculosis , caseous lymphadenitis , dna vaccination , microbiology and biotechnology , virology , adjuvant , immunization , protein subunit , biology , epitope , antigen , gene , immunology , biochemistry , genetics , bacteria

We tested the efficacy of the esterase encoded by cp1002_RS09720 from Corynebacteriumpseudotuberculosis in recombinant subunit and DNA caseous lymphadenitis (CLA) vaccines. This target was predicted as one of the best CLA vaccine candidates by mature epitope density analysis.

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