Open AccessIdentification of a distinctive phenotype for endocarditis-associated clonal complex 22 MRSA isolates with reduced vancomycin susceptibility
Author(s) -
Helene Marbach,
Eve Boakes,
Steven Lynham,
Malcolm Ward,
Jonathan A. Otter,
Jonathan D. Edgeworth
Publication year - 2017
Publication title -
journal of medical microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.91
H-Index - 117
eISSN - 1473-5644
pISSN - 0022-2615
DOI - 10.1099/jmm.0.000470
Subject(s) - microbiology and biotechnology , staphylococcus aureus , virulence , vancomycin , infective endocarditis , endocarditis , biology , phenotype , bacteria , medicine , gene , genetics , surgery
We previously identified an association between CC22 meticillin-resistant Staphylococcus aureus (MRSA) bloodstream infection isolates with an elevated vancomycin MIC (V-MIC) in the susceptible range (1.5-2 mg l-1) and endocarditis. This study explores whether these isolates have a specific phenotype consistent with the clinical findings.
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