m6A RNA methylation, a new hallmark in virus-host interactions | Zendy

Michèle Brocard | Zendy; Alessia Ruggieri | Zendy; Nicolas Locker | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

m6A RNA methylation, a new hallmark in virus-host interactions

Author(s) -

Michèle Brocard,

Alessia Ruggieri,

Nicolas Locker

Publication year - 2017

Publication title -

journal of general virology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.55

H-Index - 167

eISSN - 1465-2099

pISSN - 0022-1317

DOI - 10.1099/jgv.0.000910

Subject(s) - biology , rna , rna methylation , epigenetics , methylation , genetics , virology , computational biology , gene , methyltransferase

The role of m6A methylation of RNA has remained elusive for decades, but recent technological advances are now allowing the mapping of the m6A methylation landscape at nucleotide level. This has spurred an explosion in our understanding of the role played by RNA epigenetics in RNA biology. m6A modifications have been tied to almost every aspect of the mRNA life cycle and it is now clear that RNA virus genomes are subject to m6A methylation. These modifications play various roles in the viral replication cycle. This review will summarize recent breakthroughs concerning m6A RNA modification and their implications for cellular and viral RNAs.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research