Open AccessThe detection and avoidance of false-positive reactions in tests for rubella-specific IgM
Author(s) -
J Pattison,
J E Mace,
D. S. Dane
Publication year - 1976
Publication title -
journal of medical microbiology/journal of medical microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.91
H-Index - 117
eISSN - 1473-5644
pISSN - 0022-2615
DOI - 10.1099/00222615-9-3-355
Subject(s) - rubella , immunology , immunoglobulin m , rubella virus , microbiology and biotechnology , false negative reactions , hemagglutination , virology , medicine , biology , immunoglobulin g , antibody , vaccination , measles
Serum specimens tested for rubella-specific IgM by the haemagglutination-inhibition technique may give false-positive results due to (a) storage at -20 degrees C, (b) bacterial contamination, or (c) inactivation at 56 degrees C. These false-positive reactions can be distinguished from rubella-specific IgM activity by their resistance to 2-ME.