Open AccessLocation of the coagulase gene in Staphylococcus aureus
Author(s) -
Joseph T. Parisi,
Jack N. Baldwin,
Margaret Sottile,
Laetitia Vidal
Publication year - 1976
Publication title -
journal of medical microbiology/journal of medical microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.91
H-Index - 117
eISSN - 1473-5644
pISSN - 0022-2615
DOI - 10.1099/00222615-9-1-111
Subject(s) - coagulase , transduction (biophysics) , staphylococcus aureus , microbiology and biotechnology , mutant , biology , gene , staphylococcus epidermidis , staphylococcus , genetics , bacteria , biochemistry
Evidence is presented for the chromosomal location of the coagulase determinant in most strains of Staphylococcus aureus. By the use of a pour-plate technique, transduction of the capacity to produce coagulase to a coagulase-negative mutant of S. aureus was studied. The frequencies of transduction were low unless the transducing phage was exposed to ultraviolet irradiation and the recipient was lysogenised with the transducing phage. Attempts to transfer the coagulase gene from S. aureus to S. epidermidis were not successful.