Open AccessInhibition of Cryptococcus Neoformans by Pseudomonas Aeruginosa
Author(s) -
C. H. Teoh-Chan,
Pui Hing Chau,
M. H. Ng,
Pui Ching Wong
Publication year - 1975
Publication title -
journal of medical microbiology/journal of medical microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.91
H-Index - 117
eISSN - 1473-5644
pISSN - 0022-2615
DOI - 10.1099/00222615-8-1-77
Subject(s) - cryptococcus neoformans , pseudomonas aeruginosa , pyocyanin , microbiology and biotechnology , extracellular , agar , incubation , cryptococcus , pseudomonas , biology , pseudomonadaceae , chemistry , agar plate , bacteria , biochemistry , virulence , genetics , quorum sensing , gene
Pseudomonas aeruginosa was found to produce a factor or factors that inhibited Cryptococcus neoformans and appeared to be extracellular because the anti-C. neoformans activity was readily demonstrable in medium after the removal and killing of Pseudomonas organisms. Production of the inhibitor material was greatest in DST Agar after prolonged incubation and was reduced in the presence of glucose. A part of the inhibitory material was found to be chromatographically distinct from pyocyanin.