Evaluation of different techniques in the diagnosis of Toxoplasma encephalitis | Zendy

Juan Carlos Rodrı́guez | Zendy; M. M. MARTINEZ | Zendy; Ana Martínez | Zendy; Gloria Royo | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Evaluation of different techniques in the diagnosis of Toxoplasma encephalitis

Author(s) -

Juan Carlos Rodrı́guez,

M. M. MARTINEZ,

Ana Martínez,

Gloria Royo

Publication year - 1997

Publication title -

journal of medical microbiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.91

H-Index - 117

eISSN - 1473-5644

pISSN - 0022-2615

DOI - 10.1099/00222615-46-7-597

Subject(s) - polymerase chain reaction , avidity , antigen , virology , toxoplasmosis , parasitology , antibody , encephalitis , immunology , biology , medicine , pathology , gene , virus , genetics

This study evaluated the detection of antibodies, circulating antigens and parasite DNA by polymerase chain reaction (PCR) in the diagnosis of toxoplasma encephalitis. The detection of antibody classes and IgG avidity were not useful diagnostically. The detection of circulating antigens by the ELISA system described was not sufficiently sensitive. The detection of DNA by PCR was the most useful test especially in untreated patients, with a sensitivity of 62% overall, 81% in untreated patients and only 20% in treated patients. The use of non-isotopic probes makes the use of this technique feasible in routine diagnostic parasitology laboratories.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research