Open AccessPotentiation of the effects of chlorhexidine diacetate and cetylpyridinium chloride on mycobacteria by ethambutol
Author(s) -
S.J. Broadley,
Peter Jenkins,
J. R. Furr,
A. D. Russell
Publication year - 1995
Publication title -
journal of medical microbiology/journal of medical microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.91
H-Index - 117
eISSN - 1473-5644
pISSN - 0022-2615
DOI - 10.1099/00222615-43-6-458
Subject(s) - cetylpyridinium chloride , ethambutol , mycobacterium bovis , chlorhexidine , microbiology and biotechnology , antimicrobial , mycobacterium avium complex , mycobacterium , chemistry , rifampicin , pharmacology , antibiotics , medicine , biology , biochemistry , mycobacterium tuberculosis , tuberculosis , pathology , dentistry , pulmonary surfactant
Ethambutol enhanced the effects of chlorhexidine diacetate and cetylpyridinium chloride against Mycobacterium avium, M. bovis BCG, M. fortuitum and M. phlei. The findings show that it is possible to increase the susceptibility of mycobacteria to agents that normally exhibit poor activity against these organisms because of their reduced cellular penetration.