Open AccessPathogenic synergy between Escherichia coli and Bacteroides fragilis: studies in an experimental mouse model
Author(s) -
A. M. J. J. Verweij-Van Vught,
F. Namavar,
M. Sparrius,
W. A. C. Vel,
D. M. Maclaren
Publication year - 1985
Publication title -
journal of medical microbiology/journal of medical microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.91
H-Index - 117
eISSN - 1473-5644
pISSN - 0022-2615
DOI - 10.1099/00222615-19-3-325
Subject(s) - bacteroides fragilis , escherichia coli , microbiology and biotechnology , biology , pathogenic escherichia coli , escherichia , bacteroides , bacteroidaceae , pathogenic bacteria , enterobacteriaceae , bacteria , animal model , antibiotics , gene , biochemistry , genetics , endocrinology
An animal model is described for quantitative evaluation of pathogenic synergy between Escherichia coli and Bacteroides fragilis in which adjuvants were not required for abscess formation. Two sets of strains of E. coli and B. fragilis isolated from human wound infections were tested. Pathogenic synergy was observed in only one of the two combinations and was dependent on properties of E. coli.