Open AccessThe role of different K antigens of Escherichia coli in phagocytosis by polymorphonuclear leukocytes
Author(s) -
A. M. J. J. Verweij-Van Vught,
F. Namavar,
P. G. H. Peerbooms,
M. Sparrius,
D. M. Maclaren
Publication year - 1984
Publication title -
journal of medical microbiology/journal of medical microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.91
H-Index - 117
eISSN - 1473-5644
pISSN - 0022-2615
DOI - 10.1099/00222615-17-2-141
Subject(s) - escherichia coli , phagocytosis , antigen , microbiology and biotechnology , pilus , complement system , granulocyte , biology , bacteria , chemistry , immunology , immune system , biochemistry , gene , genetics
The importance of K antigens from six strains of Escherichia coli for the interaction with polymorphonuclear leukocytes (PMNL) was studied. The major factor influencing this interaction was the ability of strains to activate complement by the classical route during opsonisation, this process being reduced for most K-positive strains. Interference of K antigens with the functioning of common pili as adhesions of eukaryotic cells was not observed nor a toxic effect of K antigens on PMNL.