Open AccessThe role of trace elements and phosphates in the synthesis of vascular-permeability factor by Vibrio cholerae
Author(s) -
Sagar Ik,
Nagesha Cn,
Bhat Jv
Publication year - 1981
Publication title -
journal of medical microbiology/journal of medical microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.91
H-Index - 117
eISSN - 1473-5644
pISSN - 0022-2615
DOI - 10.1099/00222615-14-3-243
Subject(s) - vibrio cholerae , zinc , strain (injury) , magnesium , manganese , phosphate , permeability (electromagnetism) , chemistry , microbiology and biotechnology , trace element , bacteria , biology , biochemistry , membrane , organic chemistry , anatomy , genetics
Trace element and phosphate requirements for the synthesis of vascular-permeability factor (PF) by Vibrio cholerae strains B1307 and VC12 were investigated. While magnesium appeared to be indispensable for strain VC12, small amounts of PF were synthesised by strain B1307 in the presence of iron, zinc and manganese. However, even in the latter strain, maximum synthesis was recorded only in magnesium-containing media. Phosphates in the range 0.75-6.00mM controlled the synthesis of PF by both strains.