The Effect of Amino-Acids and Other Substances on the Activity of Streptococcal Hyaluronidase;: With a Note on the Activity of Fractions obtained during the Isolation and Purification of Components of Streptococcal Hyaluronidase | Zendy

Nuala Crowley | Zendy

Open Access

The Effect of Amino-Acids and Other Substances on the Activity of Streptococcal Hyaluronidase;: With a Note on the Activity of Fractions obtained during the Isolation and Purification of Components of Streptococcal Hyaluronidase

Author(s) -

Nuala Crowley

Publication year - 1951

Publication title -

journal of general microbiology

Language(s) - English

Resource type - Journals

eISSN - 2059-9323

pISSN - 0022-1287

DOI - 10.1099/00221287-5-5-906

Subject(s) - valine , biochemistry , methionine , cysteine , incubation , cystine , chemistry , serine , pantothenic acid , alanine , amino acid , enzyme , vitamin

SUMMARY: The titre of streptococcal polysaccharidase was increased by incubation with β-alanine, serine, tyrosine, cystine, cysteine or methionine. Dextrinogenic amylase and hyaluronidase measured by a turbidity end-point were both activated by cysteine, cystine, serine or methionine. Polysaccharidase activity also increased after incubation with hyaluronic acid, starch, pectin or dextran. Pantothenic acid suppressed activity of SH-activated enzymes, and the rise of titre observed during incubation with substrate was decreased twofold or fourfold by addition of valine. The activation of streptococcal proteinase by cysteine was also prevented or retarded by pantothenic acid or valine. Pantothenyl alcohol was more active than either pantothenate (dl-calcium salt)ordl-valine.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research