Clinical study in phase- contrast mammography: image-quality analysis | Zendy

Renata Longo | Zendy; M. Tonutti | Zendy; Luigi Rigon | Zendy; Fulvia Arfelli | Zendy; Diego Dreossi | Zendy; E. Quai | Zendy; Fabrizio Zanconati | Zendy; E. Castelli | Zendy; Giuliana Tromba | Zendy; Maria Assunta Cova | Zendy

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Clinical study in phase- contrast mammography: image-quality analysis

Author(s) -

Renata Longo,

M. Tonutti,

Luigi Rigon,

Fulvia Arfelli,

Diego Dreossi,

E. Quai,

Fabrizio Zanconati,

E. Castelli,

Giuliana Tromba,

Maria Assunta Cova

Publication year - 2014

Publication title -

philosophical transactions of the royal society a mathematical physical and engineering sciences

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.074

H-Index - 169

eISSN - 1471-2962

pISSN - 1364-503X

DOI - 10.1098/rsta.2013.0025

Subject(s) - mammography , synchrotron radiation , digital mammography , beamline , medicine , medical physics , image quality , radiology , synchrotron , phase contrast imaging , breast imaging , nuclear medicine , phase contrast microscopy , optics , physics , breast cancer , computer science , artificial intelligence , beam (structure) , cancer , image (mathematics)

The first clinical study of phase-contrast mammography (PCM) with synchrotron radiation was carried out at the Synchrotron Radiation for Medical Physics beamline of the Elettra synchrotron radiation facility in Trieste (Italy) in 2006-2009. The study involved 71 patients with unresolved breast abnormalities after conventional digital mammography and ultrasonography exams carried out at the Radiology Department of Trieste University Hospital. These cases were referred for mammography at the synchrotron radiation facility, with images acquired using a propagation-based phase-contrast imaging technique. To investigate the contribution of phase-contrast effects to the image quality, two experienced radiologists specialized in mammography assessed the visibility of breast abnormalities and of breast glandular structures. The images acquired at the hospital and at the synchrotron radiation facility were compared and graded according to a relative seven-grade visual scoring system. The statistical analysis highlighted that PCM with synchrotron radiation depicts normal structures and abnormal findings with higher image quality with respect to conventional digital mammography

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