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Quantitative photoacoustic tomography
Author(s) -
Zhen Yuan,
Huabei Jiang
Publication year - 2009
Publication title -
philosophical transactions of the royal society a mathematical physical and engineering sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.074
H-Index - 169
eISSN - 1471-2962
pISSN - 1364-503X
DOI - 10.1098/rsta.2009.0083
Subject(s) - photoacoustic tomography , photoacoustic imaging in biomedicine , tomography , computer science , multispectral image , algorithm , finite element method , reconstruction algorithm , iterative reconstruction , acoustics , biomedical engineering , materials science , optics , computer vision , physics , thermodynamics , medicine
In this paper, several algorithms that allow for quantitative photoacoustic reconstruction of tissue optical, acoustic and physiological properties are described in a finite-element method based framework. These quantitative reconstruction algorithms are compared, and the merits and limitations associated with these methods are discussed. In addition, a multispectral approach is presented for concurrent reconstructions of multiple parameters including deoxyhaemoglobin, oxyhaemoglobin and water concentrations as well as acoustic speed. Simulation and in vivo experiments are used to demonstrate the effectiveness of the reconstruction algorithms presented.

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