The pharmacology of pseudaconitine and japaconitine considered in relation to that of aconitine

In a previous paper on the Pharmacology of Aconitine and some of its principal derivatives, we have given an account of the physiological action of this, the highly toxic alkaloid of Monkshood (Aconitum Napellus ), and of its principal derivatives, and we have also discussed the ascertained physiological effects of these substances in relation to their chemical constitution. The results of this investigation have proved to be of much practical importance in connection with the pharmaceutical and medical employment of aconite, especially in demonstrating the partial antagonism to aconitine of benzacomne, and in a greater degree of aconine, both of which derivatives accompany the parent alkaloid in the plant and in the pharmaceutical preparations made from it, which have been hitherto used medicinally.