VI. Contributions to our knowledge of the connexion between chemical constitution, physiological action, and antagonism
Author(s) -
T. Lauder Brunton,
John Theodore Cash
Publication year - 1883
Publication title -
proceedings of the royal society of london
Language(s) - English
Resource type - Journals
eISSN - 2053-9126
pISSN - 0370-1662
DOI - 10.1098/rspl.1883.0058
Subject(s) - iodide , bromide , antagonism , ammonium bromide , chemistry , ammonium , action (physics) , ammonium iodide , medicinal chemistry , inorganic chemistry , organic chemistry , biochemistry , physics , pulmonary surfactant , receptor , quantum mechanics
This paper is divided into several parts. In th e first the authors consider the general action of ammonium salts, and show th at the action of the ammonium is considerably modified by the acid radical with which it is combined. All the ammonium salts affect the spinal cord, motor nerves, and muscles, and in advanced poisoning tend to poison all those structures. The course of poisoning varies with the salt employed. The chloride, bromide, and iodide form a series in which a stim ulant action on the cord is best m arked in the bromide, and the paralysing action upon it and upon motor nerves most strongly in the iodide.
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