Open AccessCytochrome oxidase
Author(s) -
D. Keilin,
E. F. Hartree
Publication year - 1938
Publication title -
proceedings of the royal society of london. series b, biological sciences
Language(s) - English
Resource type - Journals
eISSN - 2053-9193
pISSN - 0080-4649
DOI - 10.1098/rspb.1938.0019
Subject(s) - indophenol , oxidizing agent , chemistry , enzyme , reagent , biochemistry , cytochrome c oxidase , oxidase test , cytochrome , organic chemistry
It was shown by Ehrlich (1885), Vernon (1911a, b ), Battelli and Stern (1912) and others* that indophenol oxidase or indophenolase is one of the most widely distributed oxidizing enzymes found in cells of aerobic organisms. The presence of this enzyme is usually recognized by the property of cells to oxidize “ nadi” reagent (dimethyl-p -phenylenediamine + α-naphthol) to indophenol orp -phenylenediam ine to a di-imine.