Open AccessThe kinetics of Hœmolysis in colloidal silicic acid—complement systems
Author(s) -
Eric Ponder
Publication year - 1933
Publication title -
proceedings of the royal society of london. series b, containing papers of a biological character
Language(s) - English
Resource type - Journals
eISSN - 2053-9185
pISSN - 0950-1193
DOI - 10.1098/rspb.1933.0012
Subject(s) - complement (music) , haemolysis , silicic acid , connection (principal bundle) , kinetics , complement system , chemistry , biology , mathematics , physics , immunology , biochemistry , classical mechanics , immune system , geometry , organic chemistry , complementation , gene , phenotype
The hæmolytic systems obtained by adding complement to red cells sensitized with colloidal silicic acid were first described by Landsteiner and Jagic in 1904, and have excited considerable interest ever since, principally because of their apparent similarity to amboceptor-complement systems. No attempt, however, has been made to investigate their kinetics (a fact which is hardly surprising in view of their extraordinary complexity), and this paper is concerned with giving an account of such results as recent methods have been successful in establishing. 1.Methods . The methods employed are essentially those developed in connection with simpler hæmolytic systems, and especially in connection with amboceptor-complement systems (Ponder, 1932,a ).