Lactic acid in mammalian cardiac muscle.— Part III. changes in hydrogen-ion concentration. (Preliminary note.) | Zendy

L. N. Katz | Zendy; Phyllis Tookey Kerridge | Zendy; C. N. H. Long | Zendy

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Lactic acid in mammalian cardiac muscle.— Part III. changes in hydrogen-ion concentration. (Preliminary note.)

Author(s) -

L. N. Katz,

Phyllis Tookey Kerridge,

C. N. H. Long

Publication year - 1925

Publication title -

proceedings of the royal society of london series b containing papers of a biological character

Language(s) - English

Resource type - Journals

eISSN - 2053-9185

pISSN - 0950-1193

DOI - 10.1098/rspb.1925.0065

Subject(s) - hydrogen ion , lactic acid , hydrogen , anaerobic exercise , ion , skeletal muscle , cardiac muscle , saline , chemistry , stimulation , rigor mortis , ph meter , biomedical engineering , materials science , biochemistry , medicine , anatomy , biology , physiology , bacteria , organic chemistry , genetics

Experiments have been made to determine (1) the hydrogen-ion concentrations of cardiac and skeletal muscle minced in the cold (a ) under normal conditions, (b )after stimulation to fatigue, and (c ) in rigor mortis, and (2) the change of hydrogen-ion concentration following the addition of known amounts of lactic acid. The measurements were made by means of the glass electrode method (Kerridge (1)). The results given are quantitatively only preliminary in character, pending (i) the repetition of the experiments on a larger number of animals, and (ii) the more accurate estimation of corrections due to dilution with saline, &c.

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