Open AccessMuscular exercise, lactic acid, and the supply and utilisation of oxygen. Part IX. —Muscular activity and carbohydrate metabolism in the normal individual
Author(s) -
Kenji Fukui
Publication year - 1925
Publication title -
proceedings of the royal society of london. series b, containing papers of a biological character
Language(s) - English
Resource type - Journals
eISSN - 2053-9185
pISSN - 0950-1193
DOI - 10.1098/rspb.1925.0024
Subject(s) - uric acid , carbohydrate , muscular fatigue , lactic acid , medicine , energy metabolism , endocrinology , carbohydrate metabolism , leg muscle , chemistry , contraction (grammar) , biochemistry , physical therapy , biology , physical medicine and rehabilitation , bacteria , genetics
It has long been discussed what substance is primarily responsible for the provision of energy in muscular contraction. The protein hypothesis of Liebig was abandoned in his later years. It was found that the greater excretion of uric acid, or the appearance of creatinin after severe exercise, was merely due to the splitting of the components of muscular tissue,i. e ., protein is not used for the provision of energy. Chauveau (1) assumed the conversion of fat into carbohydrate and a 30 percent, loss of energy in this conversion. Chauveau’s conclusion was discussed by Zuntz (2). He put forward the assumption that the muscles, whether resting or active, utilise fat and carbohydrate in the proportion in which these are presented to them.