Open AccessThe titration carve of gelatine.—Report to the medical research council
Author(s) -
Dorothy Jordan Lloyd,
Chables Mayes
Publication year - 1922
Publication title -
proceedings of the royal society of london. series b, containing papers of a biological character
Language(s) - English
Resource type - Journals
eISSN - 2053-9185
pISSN - 0950-1193
DOI - 10.1098/rspb.1922.0005
Subject(s) - hydrochloric acid , sodium hydroxide , chemistry , base (topology) , titration , colloid , hydroxide , swelling , inorganic chemistry , mathematics , materials science , organic chemistry , composite material , mathematical analysis
During the course of some work on the swelling of gelatine gels in acid and alkaline solutions, it became increasingly evident that no fully satisfactory theory of swelling could be postulated until further information had been obtained as to the quantitative relations, both general and particular, holding between the gelatine base and its combined acid in acid systems, and between the gelatine acid and its combined base in alkaline ones respectively. The work described in the following paper is an attempt to study the problem in its simplest form; namely, in a fluid system in which all the components are in solution. Hydrochloric acid and sodium hydroxide were chosen as the acid and base to use in the investigation, since both form highly ionised solutions in water, and since none of the ions resulting carry more than a single charge, thus simplifying any considerations deduced from the law of mass action. It is still an open question how far the law of mass action can be applied to colloidal solutions. It has been shown by Procter (20), Procter and Wilson (21), Wintgen and Kruger (27), that the quantitative relations found by them to exist in the combination of hydrochloric acid with gelatine, under the conditions of their experiments, fell within the general statement of the law, such combination being regarded as a simple case of salt formation. Procter considered that his results were explicable on two hypotheses: