Open AccessOn the origin and destiny of cholesterol in the animal organism. Part XII.—On the excretion of sterols in man
Author(s) -
John A. Gardner,
F. W. Fox
Publication year - 1921
Publication title -
proceedings of the royal society of london. series b, containing papers of a biological character
Language(s) - English
Resource type - Journals
eISSN - 2053-9185
pISSN - 0950-1193
DOI - 10.1098/rspb.1921.0032
Subject(s) - excretion , cholesterol , sterol , destiny (iss module) , subject (documents) , body weight , endocrinology , physiology , chemistry , medicine , zoology , biology , library science , computer science , engineering , aerospace engineering
In Part X of this series [vol. 86, p. 13 (1912)]—“On the Excretion of Cholesterol by Man”—Ellis and Gardner, from analyses of the dried fæces collected during a series of experiments, carried out by R. H. A. Plimmer, M. Dick, and E. C. Lieb, at the Institute of Physiology, University College, and published under the title of “A Metabolism Experiment, with Special Reference to Uric Acid,” came to the conclusion that in man the excretion of cholesterol in the fæces can be largely accounted for by that taken in with the food, provided that the body weight remains constant; if, however, a rapid loss in weight takes place, as in illness, the output of sterol exceeds the intake. Further work has shown that this conclusion requires modification. In the above-mentioned investigation only one subject was experimented on and the cholesterol-content of the diet was not obtained by analysis of samples of the food actually consumed by the subject under experiment, since the examination of the fæces in question was not undertaken until long after the completion of Plimmer, Dick, and Lieb’s investigation, and was of the nature of an afterthought.