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A new standard reference film for oxygen gas transmission measurements
Author(s) -
Lan-Gui Xie,
Xia Zhao,
Si-Hong Dou,
Tang Long,
Huimin Sun
Publication year - 2019
Publication title -
royal society open science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.84
H-Index - 51
ISSN - 2054-5703
DOI - 10.1098/rsos.190142
Subject(s) - calibration , homogeneity (statistics) , coulometry , oxygen , measurement uncertainty , materials science , computer science , accuracy and precision , analytical chemistry (journal) , process engineering , chemistry , chromatography , engineering , mathematics , statistics , organic chemistry , electrode , machine learning , electrochemistry
A novel reference film was characterized to improve the oxygen gas transmission measurement accuracy of plastic materials for pharmaceutical packaging. The material processing, homogeneity, stability, jointly determined value and uncertainty evaluation were discussed. The film is the first reference film characterized by multiple laboratories using both manometric and coulometric methods. The oxygen transmission rate of the reference film was 20.53 with the expanded uncertainty of 1.36. The newly characterized reference film can be used in the calibration and self-calibration of oxygen transmission measurement equipment and analytical method verification to improve the measurement accuracy and achieve traceable data.

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