Mitochondria—hubs for regulating cellular biochemistry: emerging concepts and networks | Zendy

Alexander J. Anderson | Zendy; Thomas D. Jackson | Zendy; David A. Stroud | Zendy; Diana Stojanovski | Zendy

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Mitochondria—hubs for regulating cellular biochemistry: emerging concepts and networks

Author(s) -

Alexander J. Anderson,

Thomas D. Jackson,

David A. Stroud,

Diana Stojanovski

Publication year - 2019

Publication title -

open biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.078

H-Index - 53

ISSN - 2046-2441

DOI - 10.1098/rsob.190126

Subject(s) - biology , mitochondrion , microbiology and biotechnology , function (biology) , cell , cell metabolism , systems biology , cellular metabolism , cell function , computational biology , metabolism , genetics , biochemistry

Mitochondria are iconic structures in biochemistry and cell biology, traditionally referred to as the powerhouse of the cell due to a central role in energy production. However, modern-day mitochondria are recognized as key players in eukaryotic cell biology and are known to regulate crucial cellular processes, including calcium signalling, cell metabolism and cell death, to name a few. In this review, we will discuss foundational knowledge in mitochondrial biology and provide snapshots of recent advances that showcase how mitochondrial function regulates other cellular responses.

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