Open AccessThe characteristics of nuclear membrane fluctuations in stem cells
Author(s) -
Sedigheh Ghanbarzadeh Nodehi,
G. V. Shivashankar,
Jacques Prost,
Farshid Mohammad-Rafiee
Publication year - 2021
Publication title -
journal of the royal society interface
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.655
H-Index - 139
eISSN - 1742-5689
pISSN - 1742-5662
DOI - 10.1098/rsif.2020.1010
Subject(s) - anisotropy , physics , symmetry (geometry) , nucleus , statistical physics , confocal , langevin equation , fluctuation spectrum , confocal microscopy , condensed matter physics , optics , biology , mathematics , geometry , microbiology and biotechnology
We analyse the stem cell nucleus shape fluctuation spectrum obtained from optical confocal microscopy on an hour time scale with 10 s resolution. In particular, we investigate the angular and time dependencies of these fluctuations, define appropriate correlation functions that reveal the fundamentally out of equilibrium nature of the observed fluctuations as well as their global anisotropy. Langevin equations respecting the symmetry of the system allow us to model the damped oscillatory behaviour of the time correlations.
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