A review of attenuation correction techniques for tissue fluorescence
Author(s) -
Robert S. Bradley,
MAUREEN S. THORNILEY
Publication year - 2005
Publication title -
journal of the royal society interface
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.655
H-Index - 139
eISSN - 1742-5689
pISSN - 1742-5662
DOI - 10.1098/rsif.2005.0066
Subject(s) - attenuation , medical diagnosis , computer science , absorption (acoustics) , fluorescence , biomedical engineering , optics , physics , medicine , pathology
Fluorescence intensity measurements have the potential to facilitate the diagnoses of many pathological conditions. However, accurate interpretation of the measurements is complicated by the distorting effects of tissue scattering and absorption. Consequently, different techniques have been developed to attempt to compensate for these effects. This paper reviews currently available correction techniques with emphasis on clinical application and consideration given to the intrinsic accuracy and limitations of each technique.
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