Sleep and inflammation in resilient aging | Zendy

Michael R. Irwin | Zendy

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Sleep and inflammation in resilient aging

Author(s) -

Michael R. Irwin

Publication year - 2014

Publication title -

interface focus

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.1

H-Index - 49

eISSN - 2042-8901

pISSN - 2042-8898

DOI - 10.1098/rsfs.2014.0009

Subject(s) - sleep (system call) , psychological intervention , inflammation , disease , mental health , medicine , depression (economics) , gerontology , bioinformatics , psychiatry , immunology , biology , computer science , pathology , economics , macroeconomics , operating system

Sleep quality is important to health, and increasingly viewed as critical in promoting successful, resilient aging. In this review, the interplay between sleep and mental and physical health is considered with a focus on the role of inflammation as a biological pathway that translates the effects of sleep on risk of depression, pain and chronic disease risk in aging. Given that sleep regulates inflammatory biologic mechanisms with effects on mental and physical health outcomes, the potential of interventions that target sleep to reduce inflammation and promote health in aging is also discussed.

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