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Charles Nicholas (‘Nick’) Hales was for 40 years a leading figure in UK biomedical research, and for 25 years Head of the Department of Clinical Biochemistry at Cambridge University. During a distinguished career he made major contributions to diabetes research in three quite different fields: development and application of immunoassay methods for polypeptide hormones such as insulin; elucidation of mechanisms regulating insulin secretion; and demonstration of the role of early life nutrition in the development of metabolic disease in adulthood. He had a boundless enthusiasm for science, and especially for exploring new ideas, that infected all who had the privilege of working with him.

Charles Nicholas Hales. 25 April 1935 — 15 September 2005