Open AccessAllogeneic Bone Marrow Cocultured With Human Islets Significantly Improves Islet Survival and Function In Vivo
Author(s) -
John Zq Luo,
Fang Xiong,
Ahmad Samer Al-Homsi,
Camillo Ricordi,
Liqiang Luo
Publication year - 2013
Publication title -
transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.45
H-Index - 204
eISSN - 1534-6080
pISSN - 0041-1337
DOI - 10.1097/tp.0b013e31828235c7
Subject(s) - islet , transplantation , in vivo , renal capsule , endocrinology , medicine , diabetes mellitus , bone marrow , pancreatic islets , insulin , biology , andrology , microbiology and biotechnology
A significant barrier to islet transplantation is the rapid loss of human islet function in vivo. The present study evaluates whether bone marrow (BM) could be used to support human islet survival and function in vivo.