Open AccessmiRNA Profiling Discriminates Types of Rejection and Injury in Human Renal Allografts
Author(s) -
Julia Wilflingseder,
Heinz Regele,
Paul Perco,
Alexander Kainz,
Afschin Soleiman,
Ferdinand Mühlbacher,
Bernd Mayer,
Rainer Oberbauer
Publication year - 2013
Publication title -
transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.45
H-Index - 204
eISSN - 1534-6080
pISSN - 0041-1337
DOI - 10.1097/tp.0b013e318280b385
Subject(s) - microrna , medicine , chemokine , acute tubular necrosis , gene expression profiling , immunology , biopsy , bioinformatics , inflammation , biology , kidney , pathology , gene expression , gene , biochemistry
Increasing evidence accumulates on the central involvement of microRNAs (miRNAs) in disease pathophysiology. We identified distinctly deregulated miRNAs in human renal allograft biopsies from patients undergoing acute cellular rejection, antibody-mediated rejection (ABMR), and delayed graft function (DGF).