Tolerance Induction in HLA Disparate Living Donor Kidney Transplantation by Donor Stem Cell Infusion | Zendy

Joseph R. Leventhal | Zendy; Michaël Abécassis | Zendy; Joshua Miller | Zendy; Lorenzo Gallon | Zendy; David J. Tollerud | Zendy; Mary Jane Elliott | Zendy; Larry D. Bozulic | Zendy; Christopher Houston | Zendy; Nedjema SustentoReodica | Zendy; Suzanne T. Ildstad | Zendy

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Tolerance Induction in HLA Disparate Living Donor Kidney Transplantation by Donor Stem Cell Infusion

Author(s) -

Joseph R. Leventhal,

Michaël Abécassis,

Joshua Miller,

Lorenzo Gallon,

David J. Tollerud,

Mary Jane Elliott,

Larry D. Bozulic,

Christopher Houston,

Nedjema SustentoReodica,

Suzanne T. Ildstad

Publication year - 2012

Publication title -

transplantation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.45

H-Index - 204

eISSN - 1534-6080

pISSN - 0041-1337

DOI - 10.1097/tp.0b013e3182782fc1

Subject(s) - medicine , immunosuppression , transplantation , transplantation chimera , alemtuzumab , fludarabine , thymoglobulin , immunology , tacrolimus , surgery , stem cell , cyclophosphamide , haematopoiesis , biology , chemotherapy , hematopoietic cell , genetics

We recently reported that durable chimerism can be safely established in mismatched kidney recipients through nonmyeloablative conditioning followed by infusion of a facilitating cell (FC)-based hematopoietic stem cell transplantation termed FCRx. Here we provide intermediate-term follow-up on this phase II trial.

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