Open AccessTargeting Lymphangiogenesis After Islet Transplantation Prolongs Islet Allograft Survival
Author(s) -
Na Yin,
Nan Zhang,
Jiangnan Xu,
Qingqing Shi,
Yaozhong Ding,
Jonathan S. Bromberg
Publication year - 2011
Publication title -
transplantation
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 1.45
H-Index - 204
eISSN - 1534-6080
pISSN - 0041-1337
DOI - 10.1097/tp.0b013e31821d2661
Subject(s) - lymphangiogenesis , lymphatic system , transplantation , islet , medicine , vascular endothelial growth factor c , inflammation , lymphatic vessel , cancer research , pathology , immunology , endocrinology , vascular endothelial growth factor , diabetes mellitus , vascular endothelial growth factor a , cancer , metastasis , vegf receptors
Lymphatics are important for their conduit functions of transporting antigen, immune cells, and inflammatory mediators to draining lymph nodes and to the general circulation. Lymphangiogenesis is involved in many pathologic processes; however, the roles for lymphatic responses in transplantation have not been thoroughly investigated.