Genetic Determinants of Mycophenolate-Related Anemia and Leukopenia After Transplantation | Zendy

Pamala A. Jacobson | Zendy; David Schladt | Zendy; William S. Oetting | Zendy; Robert Leduc | Zendy; W. Guan | Zendy; Arthur J. Matas | Zendy; Vishal Lamba | Zendy; Roslyn B. Man | Zendy; Bruce A. Julian | Zendy; Ajay K. Israni | Zendy

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Genetic Determinants of Mycophenolate-Related Anemia and Leukopenia After Transplantation

Author(s) -

Pamala A. Jacobson,

David Schladt,

William S. Oetting,

Robert Leduc,

W. Guan,

Arthur J. Matas,

Vishal Lamba,

Roslyn B. Man,

Bruce A. Julian,

Ajay K. Israni

Publication year - 2010

Publication title -

transplantation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.45

H-Index - 204

eISSN - 1534-6080

pISSN - 0041-1337

DOI - 10.1097/tp.0b013e318200e971

Subject(s) - leukopenia , medicine , anemia , transplantation , single nucleotide polymorphism , gastroenterology , immunology , toxicity , biology , genetics , genotype , gene

Mycophenolate-related anemia and leukopenia are well-known toxicities after transplantation. Toxicity leads to dose reduction, addition of colony-stimulating factors or erythropoietin, or discontinuation of immunosuppressive therapy. The causes of and risk factors associated with toxicity are unclear.

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