Open AccessPretransplant Kidney-Specific Treatment to Eliminate the Need for Systemic Immunosuppression
Author(s) -
Lauren Brasile,
P. Glowacki,
James Castracane,
Bart M. Stubenitsky
Publication year - 2010
Publication title -
transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.45
H-Index - 204
eISSN - 1534-6080
pISSN - 0041-1337
DOI - 10.1097/tp.0b013e3181ffba97
Subject(s) - allorecognition , immunosuppression , medicine , ex vivo , kidney , perfusion , transplantation , in vivo , kidney transplantation , urology , immunology , immune system , biology , t cell , microbiology and biotechnology
Despite significant side effects, chronic systemic immunosuppression remains the backbone of clinical transplantation. We investigated the feasibility of preventing early allorecognition in canine renal allografts using a nonsystemic pretreatment.
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