Open AccessAssessment of Cadaveric Organ Viability During Pulsatile Perfusion Using Infrared Imaging
Author(s) -
Alexander M. Gorbach,
David B. Leeser,
Hengliang Wang,
Douglas K. Tadaki,
Carlos García-Moncó Fernández,
David DeStephano,
Douglas A. Hale,
Allan D. Kirk,
Fred Gage,
Eric A. Elster
Publication year - 2009
Publication title -
transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.45
H-Index - 204
eISSN - 1534-6080
pISSN - 0041-1337
DOI - 10.1097/tp.0b013e31819e3e02
Subject(s) - pulsatile flow , cadaveric spasm , perfusion , homogeneity (statistics) , infrared , organ donation , nuclear medicine , medicine , transplantation , anatomy , mathematics , physics , optics , statistics
Assessment of pulsatile perfusion (PP) is limited to measurements of flow (V) and resistance (R). We investigated infrared (IR) imaging during PP as a means for precise organ assessment. IR was used to monitor 10 porcine kidneys during 18 hr of PP in an uncontrolled Donation after Cardiac Death model. An IR camera (Lockheed Martin) was focused on the anterior surfaces of the kidneys. The degree of temperature homogeneity was compared with standard measurements of V and R. IR thermal images correlated with V and R (R=0.92, P<0.001). IR detected an increase in homogeneity during PP by comparing standard deviation differences before and after PP (P=0.002), which was not evident by standard measurements of V and R. Finally, IR assessment allowed for measurement of dynamic changes in perfusion.