Open AccessC4d Deposition and Cellular Infiltrates as Markers of Acute Rejection in Rat Models of Orthotopic Lung Transplantation
Author(s) -
Kazunori Murata,
Takekazu Iwata,
Shinji Nakashima,
Karen Fox-Talbot,
Zhiping Qian,
David S. Wilkes,
William M. Baldwin
Publication year - 2008
Publication title -
transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.45
H-Index - 204
eISSN - 1534-6080
pISSN - 0041-1337
DOI - 10.1097/tp.0b013e31817b0b57
Subject(s) - pathology , lung , lung transplantation , transplantation , medicine , endothelium , infiltration (hvac) , staining , immunohistochemistry , flow cytometry , antibody , immunology , physics , thermodynamics , endocrinology , surgery
C4d is a useful marker of antibody-mediated rejection in cardiac and renal transplants, but clinical studies examining correlations between circulating alloantibodies, C4d deposition, and rejection in lung transplants have yielded conflicting results.